Endocrine Abstracts

We describe the use of plasmapheresis for pre-operative stabilisation in a case of refractory Grave’s thyrotoxicosis. Our case is a 21 year woman with 12 month history of severe Grave’s disease. Her serum freeT4 was >100 pmol/L (ref.range 11–24) and TSH <0.014 mU/L at diagnosis, had no goitre and negative thyroid peroxidase antibodies. Thyroid uptake scan confirmed Grave’s disease. She was treated with carbimazole 60 mg daily and propranolol. She re...

We present a case of Phaeochromocytoma co-secreting ACTH as a rare cause of Cushing’s syndrome. Our patient is a 49 year lady admitted acutely with sudden onset headache and severe hypertension. CT brain and CSF analysis were normal. Her urinary catecholamines were found to be elevated. Noradrenaline 709 and 972 nmol/ mmol of creatinine (ref range 0–48), Adrenaline 215 and 256 (ref range 0–10). CT abdomen revealed 4.2 cm left adrenal mass, MIBG scan confirmed ph...